. "Edited: D'Eustachio, P, 2009-08-20"^^ . "Reviewed: Jassal, B, 2009-08-20"^^ . "Reviewed: Hannun, YA, Luberto, C, 2009-11-18"^^ . "Authored: D'Eustachio, P, 2009-08-20"^^ . "SGPP1 and 2 (sphingosine-1-phosphate phosphatase 1 and 2) enzymes associated with the endoplasmic reticulum membrane catalyze the hydrolysis of cytosolic sphingosine 1-phosphate to form sphingosine and orthophosphate (Johnson et al. 2003; Ogawa et al. 2003)."^^ . . . . . . . "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]"^^ . . . . .