. "Reviewed: D'Eustachio, P, 2007-04-30 14:43:26"^^ . "Edited: D'Eustachio, P, 2007-02-23 20:35:09"^^ . "Authored: D'Eustachio, P, 2007-02-23 20:35:09"^^ . "3,7,24THCA (25(R) 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate), coenzyme A, and ATP react to form the CoA conjugate of 3,7,24THCA, AMP, pyrophosphate and water. This cytosolic reaction is catalyzed by SLC27A2 (VLCS). SLC27A5 (BACS) also catalyzes this reaction; the relative contributions of the two enzymes to de novo bile acid synthesis in vivo are not certain (Mihalik et al. 2002)."^^ . . . . . . . . "3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS)"^^ . "3,7,24THCA + ATP + CoASH => 3,7,24THCA-CoA + AMP + pyrophosphate + H2O (SLC27A2 \"VLCS\")"^^ . "6.2.1.3"^^ . . . . . . . .