. "Edited: D'Eustachio, P, 2007-04-21 18:31:40"^^ . "Authored: D'Eustachio, P, 2007-04-21 18:31:40"^^ . "Reviewed: Jassal, B, 2007-04-21 18:33:24"^^ . "Cholesta-5,7,24-trien-3beta-ol and NADPH + H+ react to form desmosterol and NADP+. This reaction is catalyzed by DHCR7, associated with the endoplasmic reticulum membrane. The biochemical details of the reaction are inferred from those of the reaction catalyzed by the well-studied rat enzyme (Bae et al. 1999)."^^ . . . . . . . "Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol"^^ . "cholesta-5,7,24-trien-3beta-ol + NADPH + H+ => desmosterol + NADP+"^^ . "1.3.1.21"^^ . . . . . .