. "Reviewed: Harris, RA, 2008-09-10 18:47:12"^^ . "Cytosolic fructose-1,6-bisphosphatase catalyzes the physiologically irreversible hydrolysis of fructose-1,6-bisphosphate to form fructose-6-phosphate and orthophosphate. In the body, two isoforms of the enzyme are expressed, one ubiquitous and one muscle-specific (Kikawa et al. 1997; Tillmann and Eschrich 1998)."^^ . . . . . . . "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate"^^ . "3.1.3.11"^^ . . . . .