. "Reviewed: D'Eustachio, P, 2010-05-21"^^ . "Edited: Jupe, S, 2010-05-26"^^ . "Authored: Jupe, S, 2009-02-26 15:51:29"^^ . "The liganded receptor undergoes a conformational change, generating a signal that is propagated in a manner that is not completely understood to the the G-protein. This stimulates the exchange of GDP for GTP in the G-protein alpha subunit, activating the G-protein."^^ . . . . . . . . . "Liganded Gz-activating GPCR acts as a GEF for Gz"^^ . . . . .