<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#BiochemicalReaction> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#comment> "Reviewed: Akkerman, JW, 2009-06-03"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#comment> "Edited: Jupe, S, 2009-09-09"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#comment> "The activation of adenylyl (adenylate) cyclase (AC) results in the production of adenosine-3',5'-monophosphate i.e. cyclic AMP. Humans have 9 genes encoding membrane-associated AC and one encoding a soluble AC. Two of the classes of heterotrimeric G-proteins are named according to their effect on AC; Gs stimulates all membrane-bound ACs (the s in Gs denotes AC stimulatory); the Gi class inhibits some AC isoforms, particularly 5 and 6. Beta-gamma subunits of heterotrimeric G-proteins can also regulate AC. Ca2+/Calmodulin activates some AC isoforms (1, 8 and 3) but is inhibitory to others (5 and 6)."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#comment> "Authored: Jupe, S, 2009-05-22 13:10:56"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/14993377> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/13549488> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME+DATABASE+ID_392129> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME_REACT_19249_3> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <urn:biopax:Provenance:reactome_hm_41> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <http://www.reactome.org/biopax/48887Provenance1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#displayName> "Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#eCNumber> "4.6.1.1"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887SmallMolecule1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887SmallMolecule55> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3492> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887SmallMolecule5> .