. "The liganded receptor undergoes a conformational change, generating a signal that is propagated in a manner that is not completely understood to the the G-protein. This stimulates the exchange of GDP for GTP in the G-protein alpha subunit, activating the G-protein."^^ . "Reviewed: D'Eustachio, P, 2009-03-02 09:24:35"^^ . "Authored: Jassal, B, 2009-02-13 11:37:11"^^ . "Edited: Jassal, B, 2009-02-13 11:37:11"^^ . . . . . . . . . . . . . "Liganded Gs-activating GPCR acts as a GEF for Gs"^^ . . . . .