<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#BiochemicalReaction> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#comment> "Reviewed: Huang, Tao, 2012-05-14"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#comment> "Authored: Orlic-Milacic, M, 2012-04-04"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#comment> "Edited: Jassal, B, 2012-04-10"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#comment> "SMURF1 (Ebisawa et al. 2001), SMURF2 (Kavsak et al. 2000) or NEDD4L (Kuratomi et al. 2005) ubiquitin ligases, recruited to TGF-beta receptor complex through interaction with SMAD7, ubiquitinate both SMAD7 and/or TGF-beta receptor I (TGFBR1), targeting the complex for degradation. This was inferred from experiments using a recombinant mouse Smad7 with recombinant human ubiquitin ligases and TGF-beta receptors."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/15496141> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/11163210> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/11278251> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME_REACT_121128_1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME+DATABASE+ID_2169050> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <urn:biopax:Provenance:reactome_hm_41> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <http://www.reactome.org/biopax/48887Provenance1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#displayName> "SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#eCNumber> "6.3.2.19"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887Protein19> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887Complex4167> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#participantStoichiometry> <http://www.reactome.org/biopax/48887Stoichiometry11008> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887Complex4168> .
<http://www.reactome.org/biopax/48887BiochemicalReaction3265> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887PhysicalEntity584> .