. "Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27"^^ . "Reviewed: Heldin, CH, 2008-11-23 19:29:34"^^ . "Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27"^^ . "The Src family of tyrosine kinases are characterized by a SH3 and a SH2 domain in addition to the kinase domain.Src is activated when the SH2 domain binds to autophosphorylation sites on PDGF receptors (Tyr579 and 581 in the beta-receptor, Tyr572 and 574 in the alpha receptor), in conjuction with dephosporylation of the COOH-terminal phosphorylated tyrosine 527."^^ . . . . . . . . . "SH2 domain of Src binds to the active receptor"^^ . . . .