. "Reviewed: Heldin, CH, 2008-11-23 19:29:34"^^ . "Authored: Rothfels, K, 2011-08-24"^^ . "Once phosphorylated, PLCgamma dissociates from the receptor. The active enzyme promotes intracelllular signaling by catalysing the hydrolysis of PIP2 to generate the second messengers IP3 and DAG."^^ . . . . . . "Activated PLC gamma dissociates from the PDGF receptor"^^ . . . .