. "Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27"^^ . "Reviewed: Heldin, CH, 2008-11-23 19:29:34"^^ . "Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27"^^ . "Phosphatidylinositol 3'-kinases (PI3Ks) are a family of enzymes which can phosphorylate phosphoinositides. These bind to and are activated by PDGF receptors. Tyr 740 and tyr 751 in PDGF beta-receptor, and tyr 731 and tyr 742 in PDGF alpha-receptor have been shown to be autophosphorylation sites and to bind PI3-kinase.
"^^ . . . . . . . . "PI3-kinase binds to the active receptor"^^ . . . .