. "Reviewed: Herington, AC, 2011-06-13"^^ . "Reviewed: Waters, MJ, 2011-06-23"^^ . "Authored: Jupe, S, 2010-10-14"^^ . "Edited: Jupe, S, 2011-06-10"^^ . "JAKs bind to the box1 motif (residues 297-305) of the Growth Hormone Receptor (GHR) (Argetsinger et al. 1993), a proline-rich region just inside the cell membrane. Binding is mediated largely by the JAK N-terminal FERM domain (Frank et al. 1995, He et al. 2003). JAK 2 binding enhances the stability of GHR (He et al. 2005)."^^ . . . . . . . . . "Growth hormone receptor binds JAK2"^^ . . . .