. "Edited: Jupe, S, 2010-05-17"^^ . "Reviewed: Pinteaux, E, 2010-05-17"^^ . "Authored: Ray, KP, 2010-05-17"^^ . "NFkappaB p105 protein (p105) is a precursor of the NFkappaB p50 subunit and an inhibitor of NFkappaB. The IkappaB kinase (IKK) complex phosphorylates p105 on S927 within the PEST region. TNF-alpha-induced p105 proteolysis additionally requires the phosphorylation of S932. Purified IKK (IKK1) or IKKB (IKK2) can phosphorylate both these regulatory serines in vitro."^^ . . . . . . "The IKKB complex phosphorylates NFkB p105"^^ . "2.7.11.10"^^ . . . . . . .