. "Edited: Garapati, P V, 2010-08-02"^^ . "Reviewed: Kawai, T, Akira, S, 2010-10-30"^^ . "Authored: Garapati, P V, 2010-08-02"^^ . "Phosphorylation of these transcription factors IRF3 and IRF7 results in a conformational change that allows their dimerization to form homo- or hetero dimers. Each of the three different combinations of dimers (IRF3:IRF3, IRF7:IRF7 and IRF3:IRF7) may selectively effect the transcription of IFN-alpha gene subfamilies and IFN-beta genes."^^ . . . . . . "Dimerization of Phospho IRF3 or phospho IRF7"^^ . . . . . .