. "Reviewed: Rittinger, K, 2011-06-06"^^ . "Reviewed: Wong, Edmond, 2011-06-06"^^ . "Edited: Jupe, S, 2011-04-28"^^ . "Reviewed: Kufer, TA, 2011-04-28"^^ . "p38 MAPK has 4 representative isoforms in humans, p38 alpha (Han et al. 1993), p38-beta (Jiang et al. 1996), p38-gamma (Lechner et al. 1996) and p38-delta (Hu et al. 1999). All are activated by phosphorylation on a canonical TxY motif by the dual-specificity kinase MKK6, which displays minimal substrate selectivity amongst the p38 isoforms (Zarubin & Han, 2005). p38 alpha and gamma are also activated by MKK3."^^ . "Authored: Jupe, S, 2011-04-08"^^ . . . . . . . . . . . "Activation of p38 MAPK"^^ . . . . . . .