. "Authored: Garapati, P V, 2008-12-16 11:12:19"^^ . "Edited: Garapati, P V, 2008-12-16 11:12:19"^^ . "Reviewed: Bluestone, JA, Esensten, J, 2009-06-01 18:47:33"^^ . "Vav1 serves as a GEF for Cdc42-GTPase. It interacts with and activates Cdc42. The activated Cdc42 in turn transmits its signals through the downstream target, the PAK1 kinase."^^ . . . . . . "Activation of Cdc42 by pVav1"^^ . . . . .