. "Authored: Garapati, P V, 2008-12-16 11:12:19"^^ . "Edited: Garapati, P V, 2008-12-16 11:12:19"^^ . "Reviewed: Bluestone, JA, Esensten, J, 2009-06-01 18:47:33"^^ . "CD28 is capable of binding the Src homology 3 (SH3) domains of several proteins, including Grb2. The phospho-YMNM motif in CD28's cytoplasmic domain facilitates tandem SH2\u00E2??SH3 domain binding. Grb-2 has been shown to bind to the CD28 YMNM motif with additional SH3 domain binding to the diproline motif in the C-terminal portion of the cytoplasmic domain of CD28."^^ . . . . . . . "Grb2 binds CD28"^^ . . . .