. "Authored: Garapati, P V, 2008-12-16 11:12:19"^^ . "Edited: Garapati, P V, 2008-12-16 11:12:19"^^ . "Reviewed: Bluestone, JA, Esensten, J, 2009-06-01 18:47:33"^^ . "Gads (Grb2-related adaptor protein 2) is essential for CD28 mediated NF-kB activation. This signal is mediated by the binding of Gads to the CD28 YMNM motif. The CD28 cytoplasmic PxxP motif is also required for this association."^^ . . . . . . "Gads binds CD28"^^ . . . .