. "Authored: Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10"^^ . "Reviewed: Trowsdale, J, 2008-02-26 12:02:59"^^ . "Three tyrosine residues at positions 771, 783 and 1254 in PLC-gamma1 have been identified as the sites of receptor tyrosine kinase phosphorylation. Of these Y783 and Y1254 are required for activation of PLC-gamma1. The phosphorylation of the tyrosine residues and the activation of PLC-gamma1 is mediated by both Syk tyrosine kinase ZAP-70 and Tec kinase ITK."^^ . . . . . . "Phosphorylation of PLC-gamma1"^^ . "2.7.10"^^ . . . . . . .