<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#BiochemicalReaction> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#comment> "Edited: Rothfels, K, 2012-05-16"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#comment> "Reviewed: Ezzat, S, 2012-05-15"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#comment> "Authored: Rothfels, K, 2012-02-09"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#comment> "FGFR1-amplified lung cancer and breast cancer cells show strong phosphorylation of FGFR1 and do not show elevated levels of FGF ligand, suggesting that these receptors can undergo ligand-independent activation. Phosphorylation is enhanced in the presence of exogenous ligand, supporting the notion that overexpressed FGFR1 can be activated by both ligand- and ligand-independent pathways (Koziczak, 2004; Dutt, 2008; Weiss, 2010). The biochemical consequences of overexpression of FGFR1 in other cancer types remain to be determined (reviewed in Turner and Gross, 2010; Wesche, 2011."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME_REACT_120931_1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/20094046> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/21711248> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/21666749> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/21160078> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/15116089> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME+DATABASE+ID_1982066> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <urn:biopax:Provenance:reactome_hm_41> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <http://www.reactome.org/biopax/48887Provenance1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#displayName> "Ligand-independent phosphorylation of overexpressed FGFR1"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#eCNumber> "2.7.10"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887SmallMolecule1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887Complex2228> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#participantStoichiometry> <http://www.reactome.org/biopax/48887Stoichiometry6676> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#participantStoichiometry> <http://www.reactome.org/biopax/48887Stoichiometry6677> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887SmallMolecule2> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1807> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887Complex2229> .