<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#BiochemicalReaction> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#comment> "Reviewed: Gotoh, N, 2011-08-26"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#comment> "Authored: Rothfels, K, 2011-08-15"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#comment> "The N terminal TKB domain of CBL binds to the phospho-tyrosine 55 of SPRY2, targeting SPRY2 for degradation by the 26S proteasome. Y55 is also a binding site for PP2A, which dephosphorylates numerous serine and threonine residues on SPRY2, allowing a conformational change that may promote a SPRY2:GRB2 interaction and limit the extent of MAPK activation following FGF stimulation."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/12593796> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/11053437> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME_REACT_111241_1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/12815057> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME+DATABASE+ID_1295622> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <urn:biopax:Provenance:reactome_hm_41> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <http://www.reactome.org/biopax/48887Provenance1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#displayName> "SPRY2 binds CBL"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887Protein6466> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887Complex2218> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887Complex2215> .
<http://www.reactome.org/biopax/48887BiochemicalReaction1796> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887Complex2221> .