. "Reviewed: Gotoh, N, 2011-08-26"^^ . "Reviewed: Mohammadi, M, 2007-02-06 21:44:35"^^ . "Authored: de Bono, B, 2007-01-10 10:27:18"^^ . "Edited: Jupe, S, 2010-02-03"^^ . "Tyrosine phosphorylation of SHP2 by FGFR kinase is required for activation of the phosphatase activity of SHP2 and for downstream signaling. Tyrosine phosphorylated SHP2 plays a major role in the activation of RAS-MAP kinase pathway, although the precise role is not yet clear."^^ . . . . . . . . "SHP2 is phosphorylated by activated FGFR"^^ . "2.7.10"^^ . . . . . . .