. "Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07"^^ . "Reviewed: Greene, LA, 2007-11-08 15:39:37"^^ . "The PI3K network is negatively regulated by phospholipid phosphatases that dephosphorylate PIP3, thus hampering AKT activation. The tumour supressor PTEN is the primary phospholipid phosphatase."^^ . . . . . . "PTEN dephosphorylates PIP3"^^ . "3.1.3.67"^^ . . . . .