. "Authored: Charalambous, M, 2005-01-07 11:17:43"^^ . "Edited: Schmidt, EE, 0000-00-00 00:00:00"^^ . "14-3-3 has been displaced from Ser259. 14-3-3 may now bind its higher affinity Ser621 (S2) site. This stabilises an 'open' Raf-1 conformation that is catalytically active, and bound to p21ras via both p21ras-binding domains, CRD and RBD."^^ . . . . . . "Stabilisation of RAS:RAF by 14-3-3"^^ . . . .