. "Viral protein involved in inhibiting host transcription to ensure the shutoff of cellular proteins expression and give virus transcripts a competitive edge for access to the cellular translation machinery. Preventing the expression of host proteins is also a strategy to counteract the antiviral response. Inhibition of transcription can be performed by interfering with host RNA pol-II function or interfering with general transcription factors." . . "Host transcription shutoff by virus" . . . .