. "Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines." . . . "suppression by virus of host MDA-5 activity" . "inhibition of host IFIH1/MDA5 by virus" . "Inhibition of host MDA5 by virus" . . .