. "Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery." . . . "RNA polymerase II transcription cofactor activity" . "RNA polymerase II transcription mediator activity" . "RNA polymerase II transcriptional co-regulator" . "RNA polymerase II transcriptional cofactor activity" . "thyroid receptor-associated protein" . "TRAP protein" . . . . . .