. "DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA." . "Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15)." . "Some helicases unwind DNA as well as RNA (4,9)." . "May be identical with EC 3.6.4.13 (RNA helicase)." . . . "DNA helicase" . "ATP + H(2)O = ADP + phosphate." .