. "An endoribonuclease that cleaves double-stranded RNA molecules." . "The cleavage can be either a single-stranded nick or double-stranded break in the RNA, depending in part upon the degree of base-pairing in the region of the cleavage site." . "Specificity is conferred by negative determinants, i.e., the presence of certain Watson-Crick base-pairs at specific positions that strongly inhibit cleavage." . "RNase III is involved in both rRNA processing and mRNA processing and decay." . . . "Ribonuclease 3" . "Ribonuclease III" . "RNase III" . "Endonucleolytic cleavage to 5'-phosphomonoester." .