. "The enzyme from Pyrococcus furiosus is highly specific for D-glucose; there is some activity with 2-deoxy-D-glucose, but no activity with D-fructose, D-mannose or D-galactose as the substrate." . "No activity is detected when ADP is replaced by ATP, GDP, phosphoenolpyruvate, diphosphate or polyphosphate." . . . "ADP-dependent glucokinase" . "ADP-specific glucokinase" . "ADP + D-glucose = AMP + D-glucose 6-phosphate." . "Magnesium" .