. "This enzyme, along with EC 2.5.1.58 and EC 2.5.1.59, constitutes the protein prenyltransferase family of enzymes." . "Attaches geranylgeranyl groups to two C-terminal cysteines in Ras-related GTPases of a single family, the Rab family (Ypt/Sec4 in lower eukaryotes) that terminate in XXCC, XCXC and CCXX motifs." . "Reaction is entirely dependent on the Rab substrate being bound to Rab escort protein (REP)." . "Post-translational modification with the geranylgeranyl moiety is essential for Rab GTPases to be able to control the processes of membrane docking and fusion." . . . "Rab geranylgeranyltransferase" . "Protein geranylgeranyltransferase type II" . "GGTaseII" . "RabGGTase" . "Type II protein geranyl-geranyltransferase" . "Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate." .