. "The enzyme specifically methylates guanine(1516) at N(2) in 16S rRNA." . . . "16S rRNA (guanine(1516)-N(2))-methyltransferase" . "M(2)G(1516) methyltransferase" . "S-adenosyl-L-methionine + guanine(1516) in 16S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanine(1516) in 16S rRNA." .