. "KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine(1518) and adenine(1519) in 16S rRNA." . "Strains lacking the methylase are resistant to kasugamycin." . . . "16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase" . . "4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA." .