. "The enzyme is capable of acting on a variety of nicotinate analogs to varying degrees, including pyrazine-2-carboxylate, pyrazine 2,3-dicarboxylate, trigonelline and 6-methylnicotinate." . "The enzyme from Clostridium barkeri also possesses a catalytically essential, labile selenium that can be removed by reaction with cyanide." . "Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri." . "Other enzymes involved in this pathway are EC 1.3.7.1, EC 3.5.2.18, EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32." . . . "Nicotinate dehydrogenase" . "Nicotinate hydroxylase" . "Nicotinic acid hydroxylase" . . "Nicotinate + H(2)O + NADP(+) = 6-hydroxynicotinate + NADPH." . "Flavoprotein" . "Iron" .