. "Brings about the chlorination of a range of organic molecules, forming stable C-Cl bonds." . "Also oxidizes bromide and iodide." . "Enzymes of this type are either heme-thiolate proteins, or contain vanadate." . "A secreted enzyme produced by the ascomycetous fungus Caldariomyces fumago (Leptoxyphium fumago) is an example of the heme-thiolate type." . "It catalyzes the production of hypochlorous acid by transferring one oxygen atom from H(2)O(2) to chloride." . "At a separate site it catalyzes the chlorination of activated aliphatic and aromatic substrates, via HClO and derived chlorine species." . "In the absence of halides, it shows peroxidase (e.g. phenol oxidation) and peroxygenase activities." . "The latter inserts oxygen from H(2)O(2) into, for example, styrene (side chain epoxidation) and toluene (benzylic hydroxylation), however, these activities are less pronounced than its activity with halides." . "Has little activity with non-activated substrates such as aromatic rings, ethers or saturated alkanes." . "The chlorinating peroxidase produced by ascomycetous fungi (e.g. Curvularia inaequalis) is an example of a vanadium chloroperoxidase, and is related to bromide peroxidase (EC 1.11.1.18)." . "It contains vanadate and oxidizes chloride, bromide and iodide into hypohalous acids." . "In the absence of halides, it peroxygenates organic sulfides and oxidizes ABTS (2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid)) but no phenols." . . . "CPO" . "Chloride peroxidase" . "Chloroperoxidase" . "Vanadium haloperoxidase" . "RH + Cl(-) + H(2)O(2) = RCl + 2 H(2)O." . "Heme" .