. "TYK2 is a member of the janus protein kinase family and plays an important role in the signal transduction of various cytokines including interferon alpha/beta. Cloning and characterization of the porcine TYK2 gene revealed a conserved organization with respect to other mammalian TYK2 orthologs. The porcine gene consists of 25 exons spanning approximately 26 kb and encoding a 5.3-kb mRNA. It is located in a GC-rich and gene-rich chromosome region and contains several CpG islands. The predicted 132-kDa TYK2 protein consists of 1,184 amino acids and shows 85% identity to the human TYK2 protein. The porcine TYK2 gene was localized by FISH and RH-mapping on SSC 2q1.3-->q2.1, which is in good agreement with established human-mouse-pig comparative maps." . . "Cytogenet. Genome Res." . "Mueller M." . "Leeb T." . "Lassnig C." . "Distl O." . "Kuiper H." . "Martins-Wess F." . "2004"^^ . "103-107" . "Molecular characterization of the porcine TYK2 gene on SSC 2q1.3 -> q2.1." . "107" . "doi:10.1159/000079578" .