. "Inhibitory glycine receptor (GlyR) and GABA(A) receptor (GABA(A)R)-mediated synaptic transmission was examined in two strains of the GlyR mutant mouse spastic and the respective wild types. The mutants display a mild and a severe neurological phenotype. Electrically evoked postsynaptic whole-cell currents were recorded from alpha-motoneurons in lumbar spinal cord slices. Amplitudes of GlyR-mediated IPSCs were significantly reduced in the severe phenotype in comparison to the respective wild type and the mild phenotype mutants. Surprisingly, amplitudes of GABA(A)R-mediated IPSCs were also significantly reduced in both mutants. Fast time constants of the decay phase of IPSCs were slightly reduced for the GlyR-mediated IPSCs and significantly larger for the GABA(A)R-mediated IPSCs in both mutant strains." . . "Neurosci. Lett." . "Becker C.M." . "Becker K." . "von Wegerer J." . "Zeilhofer H.U." . "Swandulla D." . "Glockenhammer D." . "2003"^^ . "45-48" . "Spinal inhibitory synaptic transmission in the glycine receptor mouse mutant spastic." . "345" . "doi:10.1016/S0304-3940(03)00499-3" .