. "This domain is part of a cytosine specific DNA methyltransferaseenzyme. It functions non-catalytically to target the protein towards replication foci. This allows the DNMT1 protein to methylate the correct residues. This domain targets DMAP1 and HDAC2 to the replication foci during the S phase of mitosis. They are thought to have some importance in conversion of critical histone lysine moieties. [1] " . "DNMT1-RFD" . "Cytosine specific DNA methyltransferase replication foci domain" . "Mistry J, Gavin OL" . "Domain" . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .