. "\"Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.\" [GOC:dph]" . . "negative regulation of type I interferon-mediated signaling pathway" . "negative regulation of type I interferon-mediated signalling pathway" . . .