. "\"Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H(+).\" [EC:2.7.1.105, RHEA:15656]" . . "6-phosphofructo-2-kinase activity" . "6-phosphofructo-2-kinase (phosphorylating)" . "6-phosphofructose 2-kinase activity" . "ATP:beta-D-fructose-6-phosphate 2-phosphotransferase activity" . "ATP:D-fructose-6-phosphate 2-phosphotransferase activity" . "fructose 6-phosphate 2-kinase activity" . "phosphofructokinase 2 activity" . "EC:2.7.1.105" . "KEGG:R02732" . "MetaCyc:6-PHOSPHOFRUCTO-2-KINASE-RXN" . "Reactome:REACT_104172 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Saccharomyces cerevisiae\"" . "Reactome:REACT_105291 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Xenopus tropicalis\"" . "Reactome:REACT_107963 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Danio rerio\"" . "Reactome:REACT_115709 \"fructose 6-phosphate + ATP => fructose 2,6-bisphosphate + ADP, Gallus gallus\"" . "Reactome:REACT_28048 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Arabidopsis thaliana\"" . "Reactome:REACT_29034 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Drosophila melanogaster\"" . "Reactome:REACT_291 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Homo sapiens\"" . "Reactome:REACT_29935 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Rattus norvegicus\"" . "Reactome:REACT_31693 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Gallus gallus\"" . "Reactome:REACT_33667 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Dictyostelium discoideum\"" . "Reactome:REACT_34412 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Staphylococcus aureus N315\"" . "Reactome:REACT_38435 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Schizosaccharomyces pombe\"" . "Reactome:REACT_78095 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Sus scrofa\"" . "Reactome:REACT_86368 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Bos taurus\"" . "Reactome:REACT_87540 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Mus musculus\"" . "Reactome:REACT_88240 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Oryza sativa\"" . "Reactome:REACT_91876 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Taeniopygia guttata\"" . "Reactome:REACT_98327 \"D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP, Canis familiaris\"" . "RHEA:15656" . .