. . . . . . . . . . . . . . . . . . . . . . . . . "Tetherin colocalizes with HIV-1 Gag in CD81- and CD63-enriched intracellular virus-containing compartments in macrophages, and that a separate population of tetherin is located in the TGN" . "HIV-1 Gag P99A mutation reduces its co-localization with tetraspanin-enriched microdomain marker CD81 and lipid raft marker CD59" . "HIV-1 Gag proteins co-localize with CD63 and CD81 in intracellular exosomes" . "In the absence of Vpu, Env accumulates extensively within clathrin-coated endosomal structures, including the viral proteins Gag and MA; the tetraspanins CD63 and CD81; the adaptor protein complex AP-3; and AIP1/ALIX, a cellular cofactor for viral budding" . "HIV-1 Gag recruits and traps CD81 to Gag assembly sites at the plasma membrane" . "Co-fractionation" . "BioGRID" . "co-localizes with" . "recruits" . "colocalizes with" .