. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "Tetherin colocalizes with HIV-1 Gag in CD81- and CD63-enriched intracellular virus-containing compartments in macrophages, and that a separate population of tetherin is located in the TGN" . "HIV-1 Gag proteins co-localize with tetraspanins CD9, CD81, and CD82 in CD63-enriched micro domains" . "Env-mediated cell-cell fusion repression by CD9 and CD63 requires the presence of HIV-1 Gag" . "In human macrophages, HIV-1 Gag proteins co-localize with MHC II (HLA-DR), CD63, and Lamp1 in MHC II compartments" . "A dileucine-like motif (residues 321-322) in HIV-1 Gag regulates the assembly of Gag into CD63-positive multivesicular bodies" . "HIV-1 Gag proteins co-localize with CD63 and CD81 in intracellular exosomes" . "DLG1 knockdown is associated with the redistribution and colocalization of Gag toward CD63 and CD82 positive vesicle-like structures" . "The budding defect of p6-deficient HIV-1 Gag is caused primarily by C-terminal exposure of p1. The p1 domain of p6-deficient Gag acts as an inhibitory budding signal by blocking the interaction of Gag with CD63 and VPS4B" . "In the absence of Vpu, Env accumulates extensively within clathrin-coated endosomal structures, including the viral proteins Gag and MA; the tetraspanins CD63 and CD81; the adaptor protein complex AP-3; and AIP1/ALIX, a cellular cofactor for viral budding" . "In human macrophages, HIV-1 Capsid (p24) co-localizes with MHC II (HLA-DR), CD63, and Lamp1 in MHC II compartments" . "CD63 silencing inhibits production of the late protein CA p24 in early HIV-1 replication events in both macrophages and a CD4(+) cell line" . "interacts with" . "co-localizes with" . "upregulates" . "colocalizes with" .