. "FUNCTION: May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression (By similarity). SUBUNIT: Interacts with MET; oligomerization increases affinity for MET (By similarity). SUBCELLULAR LOCATION: Secreted (Potential). Apical cell membrane (By similarity). Basolateral cell membrane (By similarity). Cell projection, microvillus membrane (By similarity). TISSUE SPECIFICITY: Highly expressed in kidney. Up-regulated in renal tissues during renal injury. SEQUENCE CAUTION: Sequence=AAH26367.1; Type=Erroneous initiation; WEB RESOURCE: Name=Mucin database; URL=\"http://www.medkem.gu.se/mucinbiology/databases/\"; GENE SYNONYMS:Muc20. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License."^^ . "SEQUENCE 656 AA; 68720 MW; 5A0BECDE6F3297DA CRC64;"^^ . . . . . . . . "MUC20_MOUSE"^^ . "MUC-20"^^ . "Muc20"^^ . . "MGSVWGLAVPLLVFCWKVGVSVSSPGLDISRSVPLVTTNNMEVSTFTQRDRPSSERAFQTTNLIQYVPLDTQTLSTESASNALSATSISSEVNSRDTQTTSFVTKTRKTHTTTPAASSLEAQTTSPNLSTLNIQITSPIASSLDAQTIFPVSLSLSTQTTSPAPSFLDTQTTSPEPSSLTTSPAPSSLITSPTPSSLTTSPAPSFLDTQTTSPAPSSLTTSPAPSSLDTQTISPIELTLKTQTISTVTETRTVSIRIPSDLTVMHTIPTETLAPSNSPRTGMSTVQTGTVWDSIEAVFDTLCTDDSSEEARKITVDLLTLAHTSTEVEYLSSESSSSSDSSAGVLSSSRVLGPDSATPAKGLVAFNITHIKLSNCITEIETTITISGAPGASLSPTEATAALFTSEILTLPPPTEAKPIFPETTSLSGILSTAGTPALATTLEGTVSTSAITESETAVAQTLTSVGTSVTVRRNPLENTSTLSIETQSHTEVLGTITVPMVAGSTMGEAASFVSFTALDSSSLSVVVTTESSATSETLTTGNTTNSSFLTESHPPFSIYSTTASTSKNPNITLTKTTASPKPPTHPTTSASTAWIRKTTKHDPGEDGGFLLVRLTVASPKDLTEHNAREKLMNQLRRELHARMPLVHMSFLSIRRG"^^ . "Mucin-20"^^ .