<http://identifiers.org/uniprot/Q15398> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#ProteinReference> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#comment> "FUNCTION: Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. SUBUNIT: Interacts with CDK1. Interacts with the C-terminal proline-rich region of FBXO7. Recruited by FBXO7 to a SCF (SKP1- CUL1-F-box) protein complex in a CDK1/Cyclin B-phosphorylation dependent manner. Interacts with CDH1. SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q15398-2; Sequence=Displayed; Name=2; IsoId=Q15398-1; Sequence=VSP_015550; Note=No experimental confirmation available; TISSUE SPECIFICITY: Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta. DEVELOPMENTAL STAGE: Elevated levels of expression detected in the G2/M phase of synchronized cultures of HeLa cells. PTM: Ubiquitinated, leading to its degradation. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells. SIMILARITY: Belongs to the SAPAP family. CAUTION: It was localized to the spindle and the spindle pole (PubMed:12527899) but was later found to be localized to the spindle and to be excluded from the spindle pole (PubMed:15561729). SEQUENCE CAUTION: Sequence=BAA02797.3; Type=Erroneous initiation; Note=Translation N-terminally shortened; GENE SYNONYMS:DLGAP5 DLG7 KIAA0008. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#comment> "SEQUENCE 846 AA; 95115 MW; 588BAF238D6FFB72 CRC64;"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_Q15398> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:HGNC_HGNC%3A16864> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_Q8NG58> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:NCBI+GENE_9787> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:REFSEQ_NP_055565> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#displayName> "DLGP5_HUMAN"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#name> "HURP"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#name> "DAP-5"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#name> "Discs large homolog 7"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#name> "Disks large-associated protein DLG7"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#name> "Hepatoma up-regulated protein"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#name> "DLGAP5"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_25> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_6> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_10> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_24> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_22> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_5> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_14> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_8> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_27> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_21> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_28> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_12> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_20> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_19> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_16> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_11> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_13> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_18> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_29> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_23> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_1> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_15> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_26> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_4> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_2> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_7> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_9> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_17> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:DLGP5_HUMAN_3> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#organism> <http://identifiers.org/taxonomy/9606> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#sequence> "MSSSHFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKVGRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEGKVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAKIKGKNSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPSYTWTPLKTEVDESQATKEILAQKCKTYSTKTIQQDSNKLPCPLGPLTVWHEEHVLNKNEATTKNLNGLPIKEVPSLERNEGRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKNVFRKKVVSGIASKPKQDDAGRIAARNRLAAIKNAMRERIRQEECAETAVSVIPKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGTPKSVNKAVSQSRNEMGIPQQTTSPENAGPQNTKSEHVKKTLFLSIPESRSSIEDAQCPGLPDLIEENHVVNKTDLKVDCLSSERMSLPLLAGGVADDINTNKKEGISDVVEGMELNSSITSQDVLMSSPEKNTASQNSILEEGETKISQSELFDNKSLTTECHLLDSPGLNCSNPFTQLERRHQEHARHISFGGNLITFSPLQPGEF"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/Q15398> <http://www.biopax.org/release/biopax-level3.owl#standardName> "Disks large-associated protein 5"^^<http://www.w3.org/2001/XMLSchema#string> .