<http://identifiers.org/uniprot/P49135> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#ProteinReference> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#comment> "SEQUENCE 783 AA; 89126 MW; 6D204EF6A831D8AF CRC64;"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#comment> "FUNCTION: ATP-dependent 3'-5' DNA helicase, component of the core- TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage. CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate. SUBUNIT: One of the 6 subunits forming the core-TFIIH basal transcription factor which associates with the CAK complex composed of CDK7, CCNH/cyclin H and MNAT1 to form the TFIIH basal transcription factor. Interacts with PUF60 (By similarity). Interacts with ATF7IP (By similarity). SUBCELLULAR LOCATION: Nucleus. SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily. SIMILARITY: Contains 1 helicase ATP-binding domain. SIMILARITY: Contains 1 helicase C-terminal domain. GENE SYNONYMS:Ercc3 Xpb Xpbc. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:NCBI+GENE_13872> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:MOUSE+GENOME+DATABASE_MGI%3A95414> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:REFSEQ_NP_598419> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_P49135> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#displayName> "ERCC3_MOUSE"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#name> "3.6.4.12"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#name> "TFIIH 89 kDa subunit"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#name> "DNA excision repair protein ERCC-3"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#name> "Basic transcription factor 2 89 kDa subunit"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#name> "Xeroderma pigmentosum group B-complementing protein"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#name> "DNA repair protein complementing XP-B cells"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#name> "BTF2 p89"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#name> "Ercc3"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:ERCC3_MOUSE_1> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#organism> <http://identifiers.org/taxonomy/10090> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#sequence> "MGKRDRVDRDKKKSKKRQYEEEEEDEDDIPGNESQEAVPSAAGKQVDESSTKVDEYGAKDYRQQMPLKGDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKHNRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATELITETFTSKSAISKTAAEGSGGPSTSQGVDAQATSDIPKDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDTLNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPARMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEELAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFGSRSGQASRRCGTMSSLSGADDTVYMEYHSSRSKASSKHVHPLFKRFRK"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P49135> <http://www.biopax.org/release/biopax-level3.owl#standardName> "TFIIH basal transcription factor complex helicase XPB subunit"^^<http://www.w3.org/2001/XMLSchema#string> .