. "SEQUENCE 369 AA; 41222 MW; A78845AF74823039 CRC64;"^^ . "FUNCTION: Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. SUBUNIT: The C-terminus interacts with SHANK1 PDZ domain (By similarity). SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=A; Synonyms=SS2RA; IsoId=P30875-1; Sequence=Displayed; Name=B; Synonyms=SS2RB; IsoId=P30875-2; Sequence=VSP_001923; TISSUE SPECIFICITY: Cerebrum and kidney. SIMILARITY: Belongs to the G-protein coupled receptor 1 family. GENE SYNONYMS:Sstr2 Smstr2 Sst2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License."^^ . . . . . . . . "SSR2_MOUSE"^^ . "SS2-R"^^ . "SS2R"^^ . "SS-2-R"^^ . "SRIF-1"^^ . "Sstr2"^^ . . "MEMSSEQLNGSQVWVSSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWCVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI"^^ . "Somatostatin receptor type 2"^^ .