<http://identifiers.org/uniprot/P08842> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#ProteinReference> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#comment> "SEQUENCE 583 AA; 65492 MW; 74746AFA9D21A0A6 CRC64;"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#comment> "FUNCTION: Conversion of sulfated steroid precursors to estrogens during pregnancy. CATALYTIC ACTIVITY: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H(2)O = 3-beta-hydroxyandrost-5-en-17-one + sulfate. COFACTOR: Binds 1 calcium ion per subunit. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein. PTM: The conversion to 3-oxoalanine (also known as C- formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity (By similarity). DISEASE: Defects in STS are the cause of ichthyosis X-linked (IXL) [MIM:308100]. Ichthyosis X-linked is a keratinization disorder manifesting with mild erythroderma and generalized exfoliation of the skin within a few weeks after birth. Affected boys later develop large, polygonal, dark brown scales, especially on the neck, extremities, trunk, and buttocks. SIMILARITY: Belongs to the sulfatase family. WEB RESOURCE: Name=GeneReviews; URL=\"http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/STS\"; WEB RESOURCE: Name=Wikipedia; Note=Steroid sulfatase entry; URL=\"http://en.wikipedia.org/wiki/Steroid_sulfatase\"; GENE SYNONYMS:STS ARSC1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:REFSEQ_NP_000342> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:NCBI+GENE_412> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:RelationshipXref:HGNC_HGNC%3A11425> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_P08842> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:UNIPROT_B2RA47> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#displayName> "STS_HUMAN"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#name> "ASC"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#name> "3.1.6.2"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#name> "Steryl-sulfate sulfohydrolase"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#name> "Steroid sulfatase"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#name> "Arylsulfatase C"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#name> "STS"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#entityFeature> <urn:biopax:ModificationFeature:STS_HUMAN_1> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#organism> <http://identifiers.org/taxonomy/9606> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#sequence> "MPLRKMKIPFLLLFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTTGFKRLVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPLNCFMMRNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFAGKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRIIDGRDLMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNPVGSNGCFATHVCFCFGSYVTHHDPPLLFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHTQTLPEVPDQFSWNNFLWKPWLQLCCPSTGLSCQCDREKQDKRLSR"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://identifiers.org/uniprot/P08842> <http://www.biopax.org/release/biopax-level3.owl#standardName> "Steryl-sulfatase"^^<http://www.w3.org/2001/XMLSchema#string> .