. "FUNCTION: Glycosyltransferase involved in the elongation of O- linked ligands to activate Notch signaling. Possesses fucose- specific beta-1,3-N-acetylglucosaminyltransferase activity. CATALYTIC ACTIVITY: Transfers a beta-D-GlcNAc residue from UDP-D- GlcNAc to the fucose residue of a fucosylated protein acceptor. COFACTOR: Manganese (By similarity). SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=O00587-1; Sequence=Displayed; Name=2; IsoId=O00587-2; Sequence=VSP_042857; Note=No experimental confirmation available; SIMILARITY: Belongs to the glycosyltransferase 31 family. WEB RESOURCE: Name=GGDB; Note=GlycoGene database; URL=\"http://riodb.ibase.aist.go.jp/rcmg/ggdb/\"; WEB RESOURCE: Name=Functional Glycomics Gateway - GTase; Note=Beta-1,3-N-acetylglucosaminyltransferase manic fringe; URL=\"http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_552\"; GENE SYNONYMS:MFNG. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License."^^ . "SEQUENCE 321 AA; 36202 MW; 7CB847E7423DD0BC CRC64;"^^ . . . . . . . . . "MFNG_HUMAN"^^ . "O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase"^^ . "MFNG"^^ . "2.4.1.222"^^ . . "MQCRLPRGLAGALLTLLCMGLLCLRYHLNLSPQRVQGTPELSQPNPGPPKLQLHDVFIAVKTTRAFHRLRLELLLDTWVSRTREQTFVFTDSPDKGLQERLGSHLVVTNCSAEHSHPALSCKMAAEFDTFLASGLRWFCHVDDDNYVNPRALLQLLRAFPLARDVYVGRPSLNRPIHASEPQPHNRTRLVQFWFATGGAGFCINRKLALKMAPWASGSRFMDTSALIRLPDDCTMGYIIECKLGGRLQPSPLFHSHLETLQLLRTAQLPEQVTLSYGVFEGKLNVIKLQGPFSPEEDPSRFRSLHCLLYPDTPWCPQLGAR"^^ . "Beta-1,3-N-acetylglucosaminyltransferase manic fringe"^^ .