. "Authored: Akkerman, JW, 2009-09-04"^^ . "Reviewed: Harper, MT, 2009-11-02"^^ . "Reviewed: Poole, AW, 2009-11-02"^^ . "Reviewed: Jones, ML, 2009-11-02"^^ . "Edited: Jupe, S, 2009-11-03"^^ . "3-phosphoinositide dependent protein kinase-1 (PDK1, also known as PKB kinase because of its activity at Protein kinase B) phosphorylates T410 of Protein kinase C zeta type (PKC zeta), leading to activation. The motif surrounding T410 is highly conserved in other PKC family members suggesting that PDK1 might activate other PKCs."^^ . . . . . . "PDK1 activates PKC zeta"^^ . . . . . . . .