<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.biopax.org/release/biopax-level3.owl#BiochemicalReaction> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#comment> "The formate-tetrahydrofolate ligase activity of the trifunctional MTHFD1 enzyme catalyzes the reaction of THF polyglutamate, formate, and ATP to form 10-formylTHF polyglutamate, ADP, and orthophosphate. MTHFD1 is cytosolic and occurs as a dimer. The human enzyme has been identified and partially characterized biochemically (Hum et al. 1988); additional reaction details can be inferred from the properties of the well-studied homologous rabbit enzyme (Villar et al. 1985)."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/3871768> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#xref> <http://identifiers.org/pubmed/3053686> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME+DATABASE+ID_200711> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#xref> <urn:biopax:UnificationXref:REACTOME_REACT_11109_1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <urn:biopax:Provenance:reactome_hm_41> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#dataSource> <http://www.reactome.org/biopax/48887Provenance1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#displayName> "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#eCNumber> "6.3.4.3"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887SmallMolecule1> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887SmallMolecule1444> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#left> <http://www.reactome.org/biopax/48887SmallMolecule1971> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887SmallMolecule2> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887PhysicalEntity759> .
<http://www.reactome.org/biopax/48887BiochemicalReaction4947> <http://www.biopax.org/release/biopax-level3.owl#right> <http://www.reactome.org/biopax/48887SmallMolecule113> .
<http://www.reactome.org/biopax/48887PathwayStep6201> <http://www.biopax.org/release/biopax-level3.owl#stepProcess> <http://www.reactome.org/biopax/48887BiochemicalReaction4947> .
<http://www.reactome.org/biopax/48887Catalysis2412> <http://www.biopax.org/release/biopax-level3.owl#controlled> <http://www.reactome.org/biopax/48887BiochemicalReaction4947> .
<http://www.reactome.org/biopax/48887Pathway1162> <http://www.biopax.org/release/biopax-level3.owl#pathwayComponent> <http://www.reactome.org/biopax/48887BiochemicalReaction4947> .